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Book: Basic Cell and Molecular Biology (Bergtrom) - Biology

Book: Basic Cell and Molecular Biology (Bergtrom) - Biology


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A grasp of the logic and practice of science is essential to understand the rest of the world around us. To that end, this text remains focused on experimental support for what we know about cell and molecular biology, and on showing students the relationship of cell structure and function. Rather than trying to be a comprehensive reference book, this text selectively details investigative questions, methods and experiments that lead to our understanding of cell biology. This focus is nowhere more obvious than in the chapter learning objectives and in external links to supplementary material.

Thumbnail: A diagram of a typical prokaryotic cell. (Public Domain; Mariana Ruiz Villarreal, LadyofHats).


Bruce Alberts , Alexander Johnson , Julian Lewis , Martin Raff , Keith Roberts , and Peter Walter .

Molecular Biology of the Cell is the classic in-depth text reference in cell biology. By extracting fundamental concepts and meaning from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and illustrated with original drawings, the book is enjoyable to read, and provides a sense of the excitement of modern biology. Molecular Biology of the Cell not only sets forth the current understanding of cell biology (updated as of Fall 2001), but also explores the intriguing implications and possibilities of that which remains unknown.


Molecular Biology

Molecular Science for Drug Development and Biomedicine
by Wei-Zhu Zhong, Shufeng Zhou (eds) - MDPI AG , 2014
A rapid development has taken place in molecular science, particularly in the areas associated with drug development and biomedicine. This volume aims to further stimulate more useful findings from various approaches of molecular science.
(4670 views) RNA Interference
by Ibrokhim Y. Abdurakhmonov (ed.) - InTech , 2016
This book explains basic principles, types, and property of inducers, structural modifications, and various successful bench-to-field or clinic applications with some aspects of limitations, alternative tools, safety, and risk assessment .
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What is Life: Sub-cellular Physics of Live Matter
by Antti J. Niemi - arXiv , 2014
Proteins are the workhorses of all living organisms. From this perspective life is indeed something that can be modelled and understood using both known and still to be revealed laws that govern sub-cellular physics of live matter .
(4130 views) Using Technology to Study Cellular and Molecular Biology
- Biological Sciences Curriculum Study , 2005
The objective is to allow students to investigate how technology is used to deepen our knowledge of cellular and molecular biology. This module helps students sharpen their skills in critical thinking, experimental design, and data analysis.
(9267 views) Meiosis
by Carol Bernstein, Harris Bernstein (eds) - InTech , 2013
Meiosis is the key process underlying sexual reproduction in eukaryotes, occurring in single-celled eukaryotes and in most multicellular eukaryotes including animals and most plants. Thus meiosis is of considerable interest at the scientific level.
(7530 views) Computational Genomics
by Ron Shamir, Roded Sharan - Tel Aviv University , 2011
This course discusses algorithms for some important computational problems in Molecular Biology. In particular, we shall study problems that are pertinent to the Human Genome Project and to the so-called 'post-Genome era'.
(6975 views) Molecular Biology Web Book
by Frank Lee - Web Books Publishing , 2009
Contents: Cells and Viruses Protein Structure and Function Nucleic Acids, Genomes and Proteomics Gene Transcription Posttranscriptional Processes Cell Signaling and Apoptosis DNA Replication, Mutation and Repair Cell Division .
(12762 views) Molecular Regulation of Endocytosis
by Brian Ceresa (ed.) - InTech , 2012
This volume is a compilation of scientific 'short stories' about the entry of external substances into cells. Endocytosis regulates diverse processes such as homeostasis of the cell, signal transduction, entry of pathogens and viruses.
(9742 views) Polymerase Chain Reaction
by Patricia Hernandez-Rodriguez - InTech , 2012
This book is intended to present current concepts in molecular biology with the emphasis on the application to animal, plant and human pathology, in various aspects such as etiology, diagnosis, prognosis, treatment and prevention of diseases.
(9346 views) DNA Replication: Current Advances
by Herve Seligmann - InTech , 2011
This book will offer to its readers 30 chapters on current trends in the field of DNA replication. As several contributions in this book show, the study of DNA will continue for a while to be a leading front of scientific activities.
(10465 views) Cells: Molecules and Mechanisms
- Axolotl Academic Publishing Co. , 2010
This book was written for collegiate Cell and Molecular Biology courses and may be appropriate at both an introductory level and also as a resource for more advanced courses. The entire course is devoted to understanding the workings of the cell.
(9679 views) Baculovirus Molecular Biology
by George F Rohrmann - Bethesda , 2011
This book annotates what is known about the function of the 150 genes encoded by the genome of the baculovirus AcMNPV. The text integrates the role of the gene products in the biology of processes central to the pathology of baculoviruses.
(10271 views) The Molecular Biology of Plant Cells
by H. Smith - University of California Press , 1978
The book is intended as a text-book for senior undergraduate and post-graduate students in biology, biochemistry, botany, molecular biology and agricultural science. It covers the basic cellular physiology, biochemistry and genetics of plant cells.
(20932 views) Genetics and Molecular Biology
by Robert Schleif - The Johns Hopkins University Press , 1993
Schleif presents the fundamental concepts of molecular biology with clear explanations and critical analysis of well-chosen experiments. The result is a concise and practical approach that offers students a real understanding of the subject.
(37416 views) GRE Biochemistry, Cell and Molecular Biology Test Practice Book
- Educational Testing Service , 2008
This free GRE practice book contains one actual, full-length GRE Biochemistry, Cell and Molecular Biology Test and test-taking strategies. You can become familiar with test structure, content, test instructions and answering procedures.
(13841 views) Hepatitis C Viruses: Genomes and Molecular Biology
by Seng-Lai Tan - Taylor & Francis , 2006
The HCV genome and life cycle, the HCV core protein, glycoproteins, protease and serine protease, helicase, regulator proteins, replicon systems, regulation of host defense and adaptive immunity, vaccine design, and cell culture systems.
(13885 views) Artificial Intelligence and Molecular Biology
by Lawrence Hunter - AAAI Press , 1993
A current sampling of AI approaches to problems of biological significance. The text covers genetic sequence analysis, protein structure representation and prediction, automated data analysis aids, and simulation of biological systems.
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Educational Series: Best Free Biology Books

Biology is the study of living organisms and their structure, life-cycles, adaptations and environment.

All of the books featured below are released under an open source license.

Concepts of Biology

Concepts of Biology is designed for the introductory biology course for nonmajors taught at most two- and four-year colleges. The scope, sequence, and level of the program are designed to match typical course syllabi in the market.

Cell and Molecular Biology 2e: What We Know & How We Found Out

By Gerald Bergtrom (474 pages)

The interactive electronic text (iText) Cell and Molecular Biology 2e: What We Know & How We Found Out focuses on experimental support for what we know about cell and molecular biology.

Microbiology

Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter.

Introduction to Human Osteology

By Roberta Hall, Kenneth Beals, Holm Neumann, Georg Neumann, Gwyn Madden (131 pages)

This book is designed for use in the human osteology laboratory classroom. Bones are described to aid in identification of skeletonized remains in either an archaeological or forensic anthropology setting. Basic techniques for siding, aging, sexing, and stature estimation are described. Both images of bone and drawings are included which may be used for study purposes outside of the classroom.

Human Anatomy and Physiology Preparatory Course

By Carlos Liachovitzky (85 pages)

The overall purpose of this preparatory material is to help students familiarize with some terms and some basic concepts they will find later in the Human Anatomy and Physiology course.

General Biology

By Wikibooks.org (189 pages)

The word biology means, “the science of life”, from the Greek bios, life, and logos, word or knowledge. Therefore, Biology is the science of Living Things. That is why Biology is sometimes known as Life Science.

Biofundamentals 2.0

By Michael W. Klymkowsky & Melanie M. Cooper (253 pages)

Biology

Biology is designed to cover the scope and sequence requirements of a typical two-semester biology course for science majors. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology includes rich features that engage students in scientific inquiry, highlight careers in the biological sciences, and offer everyday applications.


Cell Biology

Cell Culture
by Radwa Ali Mehanna (ed.) - InTech , 2019
Cell culture is one of the major tools used in cellular and molecular biology, delivering an excellent model for studying the normal physiology and biochemistry of cells. This book covers some advanced aspects in cell culture methodologies.
(3036 views) Mechanisms of Mitotic Chromosome Segregation
by J. Richard McIntosh (ed.) - MDPI AG , 2017
This book describes current knowledge about the mechanisms by which cells segregate their already duplicated chromosomes in preparation for cell division. This suitable for scholars in this and related fields and for teaching at an advanced level.
(5156 views) Cell Biology
- Wikibooks , 2015
From the table of contents: Introduction to Cell Biology: What is a cell? Types of cells Preliminary Glimpse at Organelles Preliminary Glimpse at Cytoskeleton Models for Cell Biology Research Cell division Genes and more.
(8097 views)

Genetics and Biogenesis of Mitochondria and Chloroplasts
by C. William Birky, et al. - The Ohio State University Press , 1975
The genetics of chloro­plasts and mitochondrial inheritance have only fairly recently come to represent a major preoccupation of both molecular and cell biologists, who have been prompted to probe deeply into the energy-producing centers of the cell.
(6932 views) Using Technology to Study Cellular and Molecular Biology
- Biological Sciences Curriculum Study , 2005
The objective is to allow students to investigate how technology is used to deepen our knowledge of cellular and molecular biology. This module helps students sharpen their skills in critical thinking, experimental design, and data analysis.
(9267 views) Pluripotent Stem Cells
by Deepa Bhartiya, Nibedita Lenka (eds) - InTech , 2013
This book is beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing on the pluripotent stem cells biology.
(6380 views) Essentials of Cell Biology
by C.M. O'Connor, J.U. Adams - NPG Education , 2010
Essentials of Cell Biology introduces readers to the core concepts of cell biology. This course can provide an introduction to cell biology for beginning students of all ages or be a springboard to more specialized topics for advanced students.
(12364 views) Physics of Adherent Cells
by Ulrich S. Schwarz, Samuel S. Safran - arXiv , 2013
In this text, the authors give a review of recent progress in our understanding of the role of forces in cell adhesion from the viewpoint of theoretical soft matter physics and in close relation to the relevant experiments.
(5536 views) DNA Replication in Eukaryotic Cells
by Melvin L. Depamphilis (ed.) - Cold Spring Harbor Laboratory Press , 1996
The goal of this book is to provide a detailed treatment of the subject of DNA replication in eukaryotic cells. To ensure that the subject was completely presented, 92 scientists in the field of DNA replication participated in assembling this book.
(6419 views) Cellular and Molecular Neurobiology
by John H. Byrne, et al. - UTHealth , 2012
Contents: Introduction to Neurons and Neural Networks Resting Potentials & Action Potentials Ionic Mechanisms of Action Potentials Propagation of Action Potentials Synaptic Transmission at the Skeletal Neuromuscular Junction etc.
(8693 views) Cells: Molecules and Mechanisms
- Axolotl Academic Publishing Co. , 2010
This book was written for collegiate Cell and Molecular Biology courses and may be appropriate at both an introductory level and also as a resource for more advanced courses. The entire course is devoted to understanding the workings of the cell.
(9679 views) GRE Biochemistry, Cell and Molecular Biology Test Practice Book
- Educational Testing Service , 2008
This free GRE practice book contains one actual, full-length GRE Biochemistry, Cell and Molecular Biology Test and test-taking strategies. You can become familiar with test structure, content, test instructions and answering procedures.
(13841 views) Inside the Cell
- National Institutes of Health , 2005
This is an educational booklet about cell biology. It describes the processes occurring within human bodies, explores the cell and its organelles close-up. The text features cutting-edge cell biology research and techniques.
(14462 views)


Basic Methods in Molecular Biology

Basic Methods in Molecular Biology discusses the heart of the most recent revolution in biology—the development of the technology of genetics. The achievements in this field have simply changed what biologists do and, perhaps even more important, the way they think. Moreover, never before have scientists from such a broad range of disciplines rushed into such a small and slightly arcane field to learn and carry off a bit of the technology. This book comprises 21 chapters, opening with three introductory ones that discuss the basics of molecular biology the tools of the molecular biologist and general preparations, procedures, and considerations for use of the book. The following chapters then discuss cloning vectors and bacterial cells preparation of DNA from eukaryotic cells probing nucleic acids plasmid DNA preparation DNA restriction fragment preparation purification of DNA and preparation and analysis of RNA from eukaryotic cells. Other chapters cover preparation of DNA from bacteriophage clones cloning DNA from the eukaryotic genome subcloning into plasmids M13 cloning and sequencing further characterization of cloned DNA transfection of mammalian cells in culture protein methods general methods and specialized methods. This book will be of interest to practitioners in the fields of biology and molecular genetics.

Basic Methods in Molecular Biology discusses the heart of the most recent revolution in biology—the development of the technology of genetics. The achievements in this field have simply changed what biologists do and, perhaps even more important, the way they think. Moreover, never before have scientists from such a broad range of disciplines rushed into such a small and slightly arcane field to learn and carry off a bit of the technology. This book comprises 21 chapters, opening with three introductory ones that discuss the basics of molecular biology the tools of the molecular biologist and general preparations, procedures, and considerations for use of the book. The following chapters then discuss cloning vectors and bacterial cells preparation of DNA from eukaryotic cells probing nucleic acids plasmid DNA preparation DNA restriction fragment preparation purification of DNA and preparation and analysis of RNA from eukaryotic cells. Other chapters cover preparation of DNA from bacteriophage clones cloning DNA from the eukaryotic genome subcloning into plasmids M13 cloning and sequencing further characterization of cloned DNA transfection of mammalian cells in culture protein methods general methods and specialized methods. This book will be of interest to practitioners in the fields of biology and molecular genetics.


Molecular Biology

Molecular Biology, Second Edition, examines the basic concepts of molecular biology while incorporating primary literature from today’s leading researchers. This updated edition includes Focuses on Relevant Research sections that integrate primary literature from Cell Press and focus on helping the student learn how to read and understand research to prepare them for the scientific world.

The new Academic Cell Study Guide features all the articles from the text with concurrent case studies to help students build foundations in the content while allowing them to make the appropriate connections to the text. Animations provided deal with topics such as protein purification, transcription, splicing reactions, cell division and DNA replication and SDS-PAGE. The text also includes updated chapters on Genomics and Systems Biology, Proteomics, Bacterial Genetics and Molecular Evolution and RNA. An updated ancillary package includes flashcards, online self quizzing, references with links to outside content and PowerPoint slides with images.

This text is designed for undergraduate students taking a course in Molecular Biology and upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry, and Agriculture.

Molecular Biology, Second Edition, examines the basic concepts of molecular biology while incorporating primary literature from today’s leading researchers. This updated edition includes Focuses on Relevant Research sections that integrate primary literature from Cell Press and focus on helping the student learn how to read and understand research to prepare them for the scientific world.

The new Academic Cell Study Guide features all the articles from the text with concurrent case studies to help students build foundations in the content while allowing them to make the appropriate connections to the text. Animations provided deal with topics such as protein purification, transcription, splicing reactions, cell division and DNA replication and SDS-PAGE. The text also includes updated chapters on Genomics and Systems Biology, Proteomics, Bacterial Genetics and Molecular Evolution and RNA. An updated ancillary package includes flashcards, online self quizzing, references with links to outside content and PowerPoint slides with images.

This text is designed for undergraduate students taking a course in Molecular Biology and upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry, and Agriculture.


Molecular Biology of the Cell (book)

Molecular Biology of the Cell is a cellular and molecular biology textbook published by W.W. Norton & Co and currently authored by Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts and Peter Walter. The book was first published in 1983 by Garland Science and is now in its sixth edition. The molecular biologist James Watson contributed to the first three editions.

Molecular Biology of the Cell is widely used in introductory courses at the university level, being considered as a reference in many libraries and laboratories around the world. It describes the current understanding of cell biology and includes basic biochemistry, experimental methods for investigating cells, the properties common to most eukaryotic cells, the expression and transmission of genetic information, the internal organization of cells, and the behaviour of cells in multicellular organisms. [1] Molecular Biology of the Cell has been described as “the most influential cell biology textbook of its time”. [2] The sixth edition is dedicated to the memory of co-author Julian Lewis who died in early 2014.

The book was the first to position cell biology as a central discipline for biology and medicine, and immediately became a landmark textbook. [3] It was written in intense collaborative sessions in which the authors lived together over periods of time, [3] organized by editor Miranda Robertson, then Biology Editor of Nature. [4]


Molecular Biology

Molecular Biology, Third Edition, provides a thoroughly revised, invaluable resource for college and university students in the life sciences, medicine and related fields. This esteemed text continues to meet the needs of students and professors by offering new chapters on RNA, genome defense, and epigenetics, along with expanded coverage of RNAi, CRISPR, and more ensuring topical content for a new class of students. This volume effectively introduces basic concepts that are followed by more specific applications as the text evolves.

Moreover, as part of the Academic Cell line of textbooks, this book contains research passages that shine a spotlight on current experimental work reported in Cell Press articles. These articles form the basis of case studies found in the associated online study guide that is designed to tie current topics to the scientific community.

Molecular Biology, Third Edition, provides a thoroughly revised, invaluable resource for college and university students in the life sciences, medicine and related fields. This esteemed text continues to meet the needs of students and professors by offering new chapters on RNA, genome defense, and epigenetics, along with expanded coverage of RNAi, CRISPR, and more ensuring topical content for a new class of students. This volume effectively introduces basic concepts that are followed by more specific applications as the text evolves.

Moreover, as part of the Academic Cell line of textbooks, this book contains research passages that shine a spotlight on current experimental work reported in Cell Press articles. These articles form the basis of case studies found in the associated online study guide that is designed to tie current topics to the scientific community.


Table of contents (33 chapters)

Detection of Mycoplasma Contaminations

Eradication of Mycoplasma Contaminations

STR DNA Typing of Human Cell Lines: Detection of Intra- and Interspecies Cross-Contamination

Classical and Molecular Cytogenetic Analysis

MacLeod, Roderick A. F. (et al.)

Fluorescent In Situ Hybridization of DNA Probes in the Interphase and Metaphase Stages of the Cell Cycle

The Development of T Lymphocytes in Fetal Thymus Organ Culture

Generation, Isolation, and Engraftment of In Vitro-Derived Human T Cell Progenitors

In Vitro Generation of Human T Regulatory Cells: Generation, Culture, and Analysis of FOXP3-Transduced T Cells

Simultaneous Cloning and Selection of Hybridomas and Transfected Cell Lines in Semisolid Media

Isolation and Characterization of Mouse Side Population Cells

Stem Cell Identification by DyeCycle Violet Side Population Analysis

Isolation and Characterization of Cancer Stem Cells In Vitro

Ex Vivo Differentiation of Cord Blood Stem Cells into Megakaryocytes and Platelets

Generation and Characterization of Murine Alternatively Activated Macrophages

Human Long-Term Culture Initiating Cell Assay

Long-Term Culture-Initiating Cell Assay for Mouse Cells

Colony Forming Cell Assays for Human Hematopoietic Progenitor Cells

Studying Leukocyte Recruitment Under Flow Conditions

Generation and Establishment of Murine Adherent Cell Lines

Isolation, Enumeration, and Expansion of Human Mesenchymal Stem Cells in Culture

Isolation and Culture of Mesenchymal Stem Cells from Mouse Compact Bone

Generation of a Pool of Human Platelet Lysate and Efficient Use in Cell Culture

Schallmoser, Katharina (et al.)

In Vitro Methods to Culture Primary Human Breast Epithelial Cells

Human Prostate Epithelial Cell Cultures

Enzymatic Dissociation, Flow Cytometric Analysis, and Culture of Normal Mouse Mammary Tissue

Isolation and Characterization of Human Hair Follicle Epithelial Cells

Cocultivation of Human Oral Keratinocytes and Human Osteoblast-Like Cells

Isolation and Culture of Skeletal Muscle Myofibers as a Means to Analyze Satellite Cells

Hepatic Differentiation of Embryonic Stem Cells by Murine Fetal Liver Mesenchymal Cells

Methods to Culture, Differentiate, and Characterize Neural Stem Cells from the Adult and Embryonic Mouse Central Nervous System

Feeder-Independent Culture Systems for Human Pluripotent Stem Cells

Formation of Embryoid Bodies from Human Pluripotent Stem Cells Using AggreWell™ Plates


Watch the video: Bruce Alberts UCSF: Learning from Failure (February 2023).